U.S. Energy Department Launches $293 Million AI Funding Program to Accelerate Energy Innovation

The U.S. Energy Department on March 17 announced a $293 million funding opportunity aimed at advancing the Genesis Mission, a major initiative focused on applying artificial intelligence to complex national challenges across science and energy systems. The effort seeks to mobilize interdisciplinary teams to develop next-generation AI tools capable of addressing more than 20 priority areas, including advanced manufacturing, biotechnology, critical materials, nuclear energy, and quantum science.

The funding call invites participation from national laboratories, private industry, and academic institutions, signaling a broad push to integrate expertise across sectors. The program is structured in two phases to support both early-stage concepts and large-scale deployment. Initial awards ranging from $500,000 to $750,000 will fund nine-month exploratory projects. Larger follow-on awards between $6 million and $15 million will support selected projects over three years, enabling scale-up of promising solutions.

The initiative reflects a growing federal focus on leveraging AI to strengthen U.S. competitiveness in emerging technologies and to accelerate innovation in energy systems. By targeting cross-cutting challenges, the program aims to bridge gaps between scientific discovery and real-world application.

Applications for the first phase and letters of intent for the second phase are due April 28 with full applications for larger awards due May 19. The department will host an informational webinar on March 26 to guide prospective applicants.